PHYLLANTHUS-DERIVED COMPOUNDS FOR THE PREVENTION AND/OR TREATMENT OF DISEASES ASSOCIATED WITH A NUCLEOSIDIC INHIBITOR-RESISTANT RETROVIRUS OR A NON-NUCLEOSIDIC INHIBITOR-RESISTANTRETROVIRUS

摘要

The present invention relates to the use a Phyllanthus extract or a fraction thereof or a gallotannin or a combination of gallontannins for the preparati on of a pharmaceutical composition for the prevention or treatment of retroviru s related diseases associated with a nucleosidic inhibitor-resistant retroviru s and/or a non-nucleosidic inhibitor-resistant retrovirus. Preferably, the retrovirus is a human immunodeficiency virus (HIV). In accordance with the present invention, it is further preferred that said gallotannin or combination of gallotannins is or comprises corilagin and/or geraniin and another ellagitannin. Further preferred is that said Phyllanthus is Phyllanthus amarus.