Preparation of aryl compounds for use as liquid crystal materials or intermediates, by adding Grignard reagent to mixture of substituted aryl compound and nickel catalyst

摘要

In the preparation of aryl compounds (I) by cross coupling reaction of a substituted aryl compound (II) with a Grignard reagent (III) in presence of a nickel catalyst (IV), a mixture of (II) and (IV) is dosed with (III) at the reaction temperature. Independent claims are also included for: (a) the preparation of nickel catalyst precursor materials, by charging a carrier material in presence of an aqueous solution of nickel (II) salt(s) and a base; (b) the preparation of nickel catalysts (IV'), by: (i) charging a carrier material in presence of an aqueous solution of nickel (II) salt(s) and a reducing agent; or (ii) reducing a charged carrier materials obtained as in (a); and (c) the preparation of (I) from haloaromatic compounds (II') and (III), using (IV') as catalyst.