发明名称 |
Brain delivery of folic acid for the prevention of alzheimer's disease and stroke |
摘要 |
This invention provides a method of rapidly and reliably delivering folic acid, alone or in combination with other compounds, to the systemic circulation by administration via the nasal route to produce rapid onset of beneficial effects in the treatment or prevention of Alzheimer's Disease and stroke. The present invention further provides intranasal pharmaceutical compositions comprising folic acid, and/or pharmaceutically acceptable salts thereof in a variety of unique pharmaceutical dosage forms, with and without other anti-Alzheimer's or anti-stroke compounds.
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申请公布号 |
US6369058(B1) |
申请公布日期 |
2002.04.09 |
申请号 |
US20000482910 |
申请日期 |
2000.01.14 |
申请人 |
NEW MILLENNIUM PHARMACEUTICAL RESEARCH INC. |
发明人 |
HUSSAIN ANWAR A.;DITTERT LEWIS W.;TRABOULSI ASHRAF |
分类号 |
A61K31/505;A61K31/519;(IPC1-7):A61K31/495;A61K31/50 |
主分类号 |
A61K31/505 |
代理机构 |
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