| 发明名称 |
MODIFIED NODAVIRUS RNA FOR GENE DELIVERY |
| 摘要 |
The invention provides a nodavirus RNA1 molecule modified to include a heterologous insertion which is downstream of its replicase ORF and, preferably, its B2 ORF. The insertion preferably comprises one or more protein-coding regions. The modified RNA1 may be packaged in a VLP, such as a papillomavirus VLP. The small size of nodavirus RNA1 makes it ideal for HPV packaging.
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| 申请公布号 |
WO0171017(A3) |
申请公布日期 |
2002.04.04 |
| 申请号 |
WO2001IB00566 |
申请日期 |
2001.03.26 |
| 申请人 |
CHIRON SPA;BENSI, GIULIANO;ZIPPO, ALESSIO |
发明人 |
BENSI, GIULIANO;ZIPPO, ALESSIO |
| 分类号 |
C12N15/09;A61K31/7088;A61K35/76;A61K48/00;A61P43/00;C07K14/025;C07K14/16;C12N7/00;C12N7/01;C12N7/04;C12N15/86;C12P21/02;(IPC1-7):C12N15/86 |
主分类号 |
C12N15/09 |
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