发明名称 |
PROPANOIC ACID DERIVATIVES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS |
摘要 |
<p>A method for the inhibition of the binding of alpha 4 beta 1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and the use of such compounds either as above, or in formulations for the control or prevention of diseases states in which alpha 4 beta 1 is involved.</p> |
申请公布号 |
SK16092001(A3) |
申请公布日期 |
2002.04.04 |
申请号 |
SK20010001609 |
申请日期 |
2000.05.05 |
申请人 |
TEXAS BIOTECHNOLOGY CORPORATION |
发明人 |
BIEDIGER RONALD J.;HOLLAND GEORGE W.;KASSIR JAMAL M.;LI WEN;MARKET ROBERT V.;SCOTT IAN L.;WU CHENGDE |
分类号 |
C07D229/00;A61K31/192;A61K31/33;A61K31/4166;A61K31/4184;A61K31/4412;A61K31/443;A61K31/465;A61K31/497;A61K31/498;A61K31/501;A61K31/505;A61K31/517;A61P1/04;A61P3/10;A61P7/00;A61P9/10;A61P11/06;A61P17/00;A61P19/02;A61P25/00;A61P29/00;A61P37/06;C07D213/30;C07D213/64;C07D215/02;C07D235/04;C07D239/36;C07D317/60;C07D405/12;C07D409/14;(IPC1-7):C07C315/00;C07C205/00;C07C229/00;C07C321/00 |
主分类号 |
C07D229/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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