| 摘要 |
Methods of loading a substance onto an implantable device are disclosed. The implantable device may be a stent or a graft, with or without depots formed within an outer surface thereof. An exemplary method includes the act of projecting particles of the substance from a pressurized particle source onto a preselected region of the implantable device. An implantable device loaded with a substance in accordance with the method is also provided. The projected particles may be made of any substance or substances suitable for loading onto an implantable device in solid form including, but not limited to, therapeutic substances or agents, radioisotopes, radiopaque substances, polymers, proteins, and nucleic acids. Also provided is a method of loading a substance onto a stent having an outer surface with a plurality of depots formed therein. The method includes the act of projecting particles including the substance from a pressurized particle source onto the outer surface of the stent, wherein the particles are loaded into the plurality of depots. A stent loaded with a substance in accordance with the method is also provided. |
