发明名称 |
METHODS FOR THE PROPAGATION OF LYTIC ORGANISMS |
摘要 |
<p>The present invention provides a method for the propagation of lytic organisms which comprises the infection of the cells of a stable cell line within a hollow fibre bioreactor with a lytic organism, wherein after said infection, said organism multiplies within the cells and can be harvested, characteriscd in that the cell line can survive for at least ten days after said infection. The invention further provides a method as herein described wherein after harvest, the cell line is allowed to re-populate the bioreactor, and at least one subsequent harvest may be taken, with the cell line being able to repopulate the bioreactor after each harvest.</p> |
申请公布号 |
EP1192245(A2) |
申请公布日期 |
2002.04.03 |
申请号 |
EP20000943754 |
申请日期 |
2000.06.02 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
FORD, MARTIN, JAMES;HISSEY, PAUL, HENRY;PATEMAN, TONY, JAMES |
分类号 |
A61K35/76;C12N7/00;(IPC1-7):C12N7/00;C12N9/00;C07K14/00;C12N9/02;C12M3/00;C12N15/85 |
主分类号 |
A61K35/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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