发明名称 |
Monoclonal antibodies specific to VEGF receptors and uses thereof |
摘要 |
Monoclonal antibodies that specifically bind to an extracellular domain of a flt-1 receptor and neutralize activation of the receptor are provided. In vitro and in vivo methods of using these antibodies are also provided.
|
申请公布号 |
US6365157(B2) |
申请公布日期 |
2002.04.02 |
申请号 |
US19990401163 |
申请日期 |
1999.09.22 |
申请人 |
IMCLONE SYSTEMS, INC. |
发明人 |
ROCKWELL PATRICIA;GOLDSTEIN NEIL I. |
分类号 |
A61K38/00;C07K14/71;C07K16/28;C12N15/13;C12P21/08;(IPC1-7):A01N37/18 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|