| 发明名称 |
IMIDAZOLE DERIVATIVE AND ITS USE AS CYTOKINE INHIBITOR |
| 摘要 |
PROBLEM TO BE SOLVED: To provide an imidazole derivative useful for inflammatory cytokine- mediated diseases. SOLUTION: This imidazole derivative is shown by the general formula (I), specifically, e.g. 2-(4-cyanophenyl)-4-(4-fluorophenyl)-5-(4-pyridyl)-1H-imidazole, 4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-quinolyl)-1H-imidaz ole.
|
| 申请公布号 |
JP2002097189(A) |
申请公布日期 |
2002.04.02 |
| 申请号 |
JP20010237606 |
申请日期 |
2001.08.06 |
| 申请人 |
SMITHKLINE BEECHAM CORP |
发明人 |
ADAMS JERRY LEROY;GALLAGHER TIMOTHY FRANCIS;LEE JOHN C;WHITE JOHN RICHARD |
| 分类号 |
A61K31/4164;A61K31/44;A61K31/4427;A61K31/4433;A61K31/4439;A61K31/4545;A61K31/47;A61K31/4709;A61K31/4725;A61K31/496;A61K31/505;A61K31/506;A61K31/5377;A61P7/02;A61P9/00;A61P11/00;A61P11/06;A61P13/12;A61P17/06;A61P19/00;A61P19/02;A61P19/08;A61P19/10;A61P29/00;A61P31/10;A61P37/00;A61P37/06;A61P43/00;C07D233/56;C07D401/04;C07D401/14;C07D403/04;C07D409/14;C07D413/14;C07D417/14;(IPC1-7):C07D401/04;A61K31/443;A61K31/470;A61K31/537 |
主分类号 |
A61K31/4164 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
