发明名称 Methylxanthines in the diagnosis and treatment of autistic disorder
摘要 The invention is based on the discovery that the levels of one or more methylxanthines in urine samples are significantly decreased in children diagnosed with symptoms of autistic disorder, compared to the levels in normal children, and that levels of xanthines in urine are increased in autistic children. Consequently, the presence in the urine of levels of methylxanthines below a certain range and the level of xanthine above a certain range, are diagnostic of autistic disorder. In another aspect, one or more of these methylxanthines can be used to treat individuals exhibiting symptoms of autistic disorder.
申请公布号 US6365593(B2) 申请公布日期 2002.04.02
申请号 US20010834169 申请日期 2001.04.12
申请人 REPLIGEN CORPORATION 发明人 RUSCHE JAMES R.;ZHANG JUNDONG
分类号 A61K31/522;G01N33/52;G01N33/68;(IPC1-7):A61K31/52 主分类号 A61K31/522
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