发明名称 |
6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity |
摘要 |
Novel compounds which are effective PDE IV inhibitors are disclosed. The compounds possess improved PDE IV inhibition compared to theophylline or rolipram, with improved selectivity with regard to, e.g., PDE V inhibition. The present invention includes compounds of Formula I:wherein the substituents are as disclosed herein.
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申请公布号 |
US6365606(B1) |
申请公布日期 |
2002.04.02 |
申请号 |
US20000506624 |
申请日期 |
2000.02.18 |
申请人 |
EURO-CELTIQUE, S.A. |
发明人 |
CAVALLA DAVID;HOFER PETER;GEHRIG ANDRE;WINTERGERST PETER;CHASIN MARK |
分类号 |
C07D263/56;C07D413/06;C07D417/06;(IPC1-7):A61K31/440;C07D209/44;C07D401/10 |
主分类号 |
C07D263/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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