IMMOBILIZED LIPASE, METHOD FOR IMPROVING SUBSTRATE SPECIFICITY OF LIPASE AND METHOD FOR PERFORMING OPTICAL RESOLUTION

摘要

PROBLEM TO BE SOLVED: To provide a method for immobilizing a lipase while maintaining a high enzyme activity and also improving its substrate specificity for optical isomers. SOLUTION: This method for immobilizing the lipase comprises immobilizing the lipase exhibiting a substrate specificity for optical isomers in a structural unit having an inner diameter somewhat larger than that of the lipase and having a structural stability, especially preferably in pores of a meso-porous silica porous material.