| 摘要 |
Systems, methods and computer program products process genomic data by providing a hierarchy of object superclasses and subclasses that represent genomic data, each object superclass/subclass including associated variables for the genomic data and methods that are performed on the genomic data, also referred to as an object library. Messages are sent between the hierarchy of superclasses and subclasses that represent genomic data, to thereby store, recall and analyze the genomic data. Messages may be sent between the hierarchy of object superclasses and subclasses that represent genomic data in response to a user request to store, recall or analyze the genomic data. These messages also may be sent in response to automated processes that run independent of user requests to store, recall or analyze the genomic data. The messages also may be sent in response to genomic data that is obtained by crawling a network such as the World Wide Web. Messages also may be sent between the hierarchy of object superclasses and subclasses that represent genomic data, to analyze the genomic data by finding patterns of gene expression levels among genes in experiments, and/or to analyze a gene expression signature for a pathology. An instance of at least one of the object superclasses and subclasses that represent genomic data also may be generated in response to receipt of raw genomic data. The raw genomic data may be received from a user, a process that is automatically run and/or a network crawler. Gene expression levels among genes in experiments that meet a predefined percentage change in expression level between the plurality of experiments may be displayed. The patterns of gene expression levels among the genes in the experiments also may be displayed as a function of gene families to which the plurality of genes in the plurality of experiments belong. The patterns of gene expression levels among the genes in the experiments also may be displayed as a scatter plot of gene expression levels among genes in two experiments, wherein at least some of the points in the scatter plot are surrounded by an error cloud that indicates an amount of error in the two experiments. |
