| 摘要 |
The invention provides isolated nucleic acid molecules, designated PLTR-1 nucleic acid molecules, which encode novel phospholipid transporter family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PLTR-1 nucleic acid molecules, host cells into which the expression vector s have been introduced, and nonhuman transgenic animals in which a PLTR-1 gene has been introduced or disrupted. The invention still further provides isolated PLTR-1 proteins, fusion proteins, antigenic peptides and anti-PLTR-1 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided. |
