| 摘要 |
<p>The invention concerns a method for formulating one or several active substance(s) in the form of directly compressible granules comprising wet process granulation using a binding solution of said active substance and optionally associated excipients, then drying the resulting granules. The invention is characterised in that said granulation is carried out by low pressure extrusion of the mixture of the active substance(s), binding solution and optionally excipient(s).</p> |
