AMPHIPATHIC LINEAR PEPTIDES AND COMPOSITIONS CONTAINING SAME

摘要

The invention concerns peptides containing or consisting of an antibiotic peptide by (i) modification of cysteine residues so that said peptide is devoid of disulphide bond, (ii) substitution of 1 to 18 and preferably of 1 to 5 amino acids, and/or permutation of at least a pair of amino acids, said substitutions and/or permutations being such that said peptide has an amphipathic character. The invention also concerns a compound formed by at least one of said peptide directly or indirectly bound to at least an active substance.