发明名称 |
High density molecular arrays on porous surfaces |
摘要 |
The present invention provides a unique and highly accurate method for generating molecular arrays of very high density on porous surfaces. The method involves the application of focused acoustic energy to each of a plurality of fluid-containing reservoirs to eject a small fluid droplet-on the order of 1 picoliter or less-from each reservoir to a site on a porous substrate surface. High density molecular arrays are provided as well, in which greater than about 62,500 molecular moieties, serving as array elements, are present on a porous surface. Biomolecular arrays that can be generated using focused acoustic ejection include oligonucleotide arrays and peptidic arrays.
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申请公布号 |
US2002037527(A1) |
申请公布日期 |
2002.03.28 |
申请号 |
US20010964215 |
申请日期 |
2001.09.25 |
申请人 |
ELLSON RICHARD N.;MUTZ MITCHELL W.;FOOTE JAMES K. |
发明人 |
ELLSON RICHARD N.;MUTZ MITCHELL W.;FOOTE JAMES K. |
分类号 |
B01J19/00;B05B17/06;B41J2/04;B41J2/14;C07B61/00;C40B40/06;C40B40/10;C40B60/14;(IPC1-7):C12Q1/68;G01N33/543 |
主分类号 |
B01J19/00 |
代理机构 |
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