摘要 |
<p>Compounds of the general formula (|) have affinity for serotonin receptor and are useful as remedies for various central nervous system diseases: (|) wherein R1 is hydrogen; R2 is hydrogen or lower alkyl; R3 is hydrogen, -COOR12, or the like, and R4 is hydrogen, lower alkyl, or the like, or alternatively R?3 and R4¿ may be united to form =O or =S; R5 is hydrogen, or alternatively R?3 and R5¿ may be united to form a single bond; R6 is hydrogen, -COOR24, or the like; R7 is hydrogen, halogeno, lower alkyl, or the like; R8 is hydrogen, lower alkyl, cycloalkyl, or the like; and R?9, R10 and R11¿ are each independently hydrogen, halogeno, lower alkyl, or the like.</p> |