摘要 |
The invention concerns compounds of formula (I) wherein: R1 is a group of formula CnHxFy wherein: n = 1 or 2, x = 0 to 3, y = 1 to 5, and x+y = 2n+1; R2 represents a hydrogen, a C1-C4 alkyl or a halogen atom; R represents a C2-C4 alkenyl, phenyl, naphthyl, thienyl, furyl, pyrrolyl, pyridyl, imidazolyl or thiazolyl group optionally substituted by two or three R4 groups; R3 present once, twice or three times on the phenyl, and R4 represent independently of one another, a hydrogen atom, a halogen atom, a C1-C4 alkyl, hydroxy, C1-C4 alkoxy, cyano, nitro, perfluoro C1-C2 alkyl, amino, O-(C1-C2 alkyl)-NH2, SO2NH2 or hydroxymethyl group; and their salts, N-oxides and hydrates. The invention has therapeutic applications.
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申请人 |
SANOFI-SYNTHELABO;COURTEMANCHE, GILLES;CRESPIN, OLIVIER;PASCAL, CECILE |
发明人 |
COURTEMANCHE, GILLES;CRESPIN, OLIVIER;PASCAL, CECILE |