摘要 |
<p>The invention relates to compositions comprising a sodium channel inhibitor. Also provided are methods of identifying such inhibitors, as well as kits and pharmaceutical compositions containing the same. The invention also relates to methods of treating disorders associated with irregular or improper epithelial sodium channel ('ENAC') activity, including hypertension, renal insufficiency, electrolyte imbalances, cystic fibrosis, and Liddle's syndrome.</p> |