发明名称 SUBSTITUTED AMINO-AZA-CYCLOALKANES USEFUL AGAINST MALARIA
摘要 The invention relates to novel compounds which are substituted amino-aza-cycloalkane derivatives of the general formula I. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more compounds of general formula I and especially their use as inhibitors of the plasmodium falciparum protease plasmepsin II or related aspartic proteases.
申请公布号 WO0224649(A1) 申请公布日期 2002.03.28
申请号 WO2001EP10272 申请日期 2001.09.06
申请人 ACTELION PHARMACEUTICALS LTD;BOSS, CHRISTOPH;FISCHLI, WALTER;MEYER, SOLANGE;RICHARD-BILDSTEIN, SYLVIA;WELLER, THOMAS 发明人 BOSS, CHRISTOPH;FISCHLI, WALTER;MEYER, SOLANGE;RICHARD-BILDSTEIN, SYLVIA;WELLER, THOMAS
分类号 A61K31/40;A61K31/4468;A61K31/4525;A61K31/4545;A61K31/506;A61K31/55;A61K45/00;A61P33/02;A61P33/06;A61P43/00;C07D207/14;C07D211/58;C07D223/12;C07D401/06;C07D401/12;C07D405/06;C07D405/12;C07D405/14;C07D409/06;C07D409/12;C07D409/14;(IPC1-7):C07D211/58;A61K31/435 主分类号 A61K31/40
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