USE OF STATINS (HMG-COA REDUCTASE INHIBITORS) FOR THE PREPARATION OF MEDICAMENT AS A NOVEL TYPE OF IMMUNOMODULATOR, IMMUNOSUPPRESSOR ANDANTI-INFLAMMATORY AGENT

摘要

The present invention relates to methods of causing MHC-class II or CD40 mediated immunomodulation, immunosuppression and anti-inflammatory action, i n a subject suffering from or susceptible of suffering from a condition involving inappropriate immune response, which comprises administering to th e subject at least one statin, or a functionally or structurally equivalent molecule, in an amount effective to modulate MHC class II or CD40 expression in the subject.