发明名称 |
TRICYCLIC COMPOUNDS HAVING SPIRO UNION |
摘要 |
<p>This invention relates to tricyclic compounds having spiro union represented by the following formula (I) or its salt which is useful as a drug, and in particular, as an inhibitor for activated blood coagulation factor X, which can be administered orally and which exhibits strong anticoagulation action. <CHEM> The invention also relates to a pharmacophore which was derived from the compound and is useful in molecular designing of the FXa inhibitor.</p> |
申请公布号 |
EP1191028(A1) |
申请公布日期 |
2002.03.27 |
申请号 |
EP20000940912 |
申请日期 |
2000.06.30 |
申请人 |
MOCHIDA PHARMACEUTICAL CO., LTD. |
发明人 |
NISHIDA, HIDEMITSU;SAITOH, FUMIHIKO;HARADA, KOUSUKE;SHIROMIZU, IKUYA |
分类号 |
A61P7/02;A61P9/00;C07D498/20;(IPC1-7):C07D471/20;G01N33/15;G01N33/50;A61K31/541;A61K31/537;A61K31/498;C07D519/00;C07D498/10 |
主分类号 |
A61P7/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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