发明名称 |
System and method for optimization of parameters of liquid-handling instruments |
摘要 |
<p>A system and method for optimizing liquid-handling parameters for liquid-handling instruments based on automated use of Design of Experiments principles. An automated factor screening experiment generates a fractional factorial design, creates a set of liquid classes, directs a pipetting control program to execute a worklist of pipetting commands, and performs an effects analysis to determine the factors affecting pipetting precision. An automated response surface methodology experiment based on a central composite experimental design is used to determine the optimal level of factors affecting precision of pipetting. An automated range-finding experiment determines the useful volume range of the liquid class so developed. An automated accuracy calibration experiment generates a calibration coefficient for the liquid class. An automated liquid class verification experiment then evaluates the precision and accuracy of the liquid class. <IMAGE></p> |
申请公布号 |
EP1191312(A2) |
申请公布日期 |
2002.03.27 |
申请号 |
EP20010121802 |
申请日期 |
2001.09.11 |
申请人 |
TECAN TRADING AG |
发明人 |
VESSEY, ANDREW R.;PORTER, GREGORY L.;SIESEL, PETER T. |
分类号 |
B01L3/02;G01F3/22;G01F25/00;G01N35/00;G01N35/10;(IPC1-7):G01F3/22;G06F19/00 |
主分类号 |
B01L3/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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