发明名称 |
Methylated, SMD homologous peptides, reactive with the antibodies from sera of living beings affected with systemic lupus erythematosus |
摘要 |
The present invention relates to a method of producing certain peptides containing methylated arginines that are followed by a glycine residue and that constitute immunogenic determinants of antibodies present in sera from patients with systemic lupus erythematosus, or Epstein-Barr virus and wherein the methylation is a prerequisite for reacting with said antibodies. The invention also relates to the use of said peptides for diagnosis and treatment of systemic lupus erythematosus and related diseases, and diseases in which Epstein-Barr virus has been implicated.
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申请公布号 |
US6362007(B1) |
申请公布日期 |
2002.03.26 |
申请号 |
US19990297981 |
申请日期 |
1999.05.10 |
申请人 |
INNOGENETICS N.V. |
发明人 |
MEHEUS LYDIE;UNION ANN;RAYMACKERS JOSEPH;LUEHRMANN REINHARD GEORG |
分类号 |
G01N33/564;A61K38/00;A61K38/17;A61K39/00;A61K39/395;A61P29/00;A61P35/00;A61P37/00;C07K7/06;C07K7/08;C07K14/00;C07K14/47;C07K14/525;C07K14/705;C07K16/18;C07K16/42;C12N15/09;C12N15/12;C12P21/02;C12R1/01;G01N33/569;(IPC1-7):G01N33/514 |
主分类号 |
G01N33/564 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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