发明名称 |
Oxy substituted 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines |
摘要 |
Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.
|
申请公布号 |
US6362198(B1) |
申请公布日期 |
2002.03.26 |
申请号 |
US20000670846 |
申请日期 |
2000.09.27 |
申请人 |
PFIZER INC. |
发明人 |
GOLDSTEIN STEVEN W.;MAKOWSKI MICHAEL R.;RUGGERI ROGER B.;WESTER RONALD T. |
分类号 |
A61K31/4706;A61K31/4709;A61K31/5355;A61P3/04;A61P3/06;A61P9/00;A61P9/10;A61P9/12;A61P43/00;C07D215/42;C07D215/44;C07D401/12;(IPC1-7):A61K31/47 |
主分类号 |
A61K31/4706 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|