发明名称 |
Aromatic sulfonyl alpha-hydroxy hydroxamic acid compounds |
摘要 |
An aromatic sulfonyl alpha-hydroxy hydroxamic acid compound that, inter alia, inhibits matrix metalloprotease activity is disclosed, as is a treatment process that comprises administering a contemplated aromatic sulfonyl alpha-hydroxy hydroxamic acid compound in an MMP enzyme-inhibiting effective amount to a host having a condition associated with pathological matrix metalloprotease activity.
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申请公布号 |
US6362183(B1) |
申请公布日期 |
2002.03.26 |
申请号 |
US19990254535 |
申请日期 |
1999.06.04 |
申请人 |
G. D. SEARLE & COMPANY |
发明人 |
FRESKOS JOHN N.;BOEHM TERRI L.;MISCHKE BRENT V.;HEINTZ ROBERT M.;MCDONALD JOSEPH J.;DECRESCENZO GARY A.;HOWARD SUSAN C. |
分类号 |
C07C317/22;C07C317/44;C07C323/65;C07D207/16;C07D211/62;C07D213/30;C07D213/82;C07D295/15;(IPC1-7):C07D403/02;C07D403/12;C07D413/02;C07D279/12;C07D333/06 |
主分类号 |
C07C317/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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