发明名称 Peptide conjugated anti-cancer prodrugs
摘要 The present invention relates to pharmaceutical compositions comprising a targeting peptide, a protease specific cleavable peptide, and a chemotherapeutic drug that when conjugated are substantially inactive, but upon degradation of the cleavable sequence by a proteolytic enzyme abundant in or within the target cancer cell 5, the chemotherapeutic drug is released and becomes active, and to the use of these compositions for treatment of cancer.
申请公布号 AU8802501(A) 申请公布日期 2002.03.22
申请号 AU20010088025 申请日期 2001.09.05
申请人 BIOSIGHT LTD. 发明人 STELA GENGRINOVITCH
分类号 A61K38/06;A61K38/08;A61K38/10;A61K38/17;A61K47/48 主分类号 A61K38/06
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