METHOD OF MAKING A VACCINE

摘要

A method of making a vaccine from a protective antigen. The protective antigen is useful against Bacillus anthracis. The protective antigenis produced by an asporogenic organism which overpoduces the desired antigen. The asporogenic organism is a recombinant asporogenic B. anthracis. The recombinant asporogenic B. anthracis was derived from a DELTASterne-1(pPA102) strain of bacteria and binds to dye when grown on Congo Red Agar.