发明名称 |
Transdermal patch for delivery of non-steroidal antiinflammatory agent, containing e.g. alkyl-pyrrolidone, metal salt, surfactant and polymers, provides good drug release and absorption properties |
摘要 |
A transdermal drug delivery patch comprises: (a) a non-steroidal antiinflammatory agent; (b) an alkyl-pyrrolidone; (c) hydrophilic polyethylene glycol; (d) a hydrophilic nonionic surfactant; (e) a water-soluble carboxylated polymer; (f) a water-soluble vinyl polymer; (g) a water-insoluble polyvalent metal salt; (h) a polyol; (i) an organic hydroxyacid; and (j) water. A transdermal drug delivery patch comprises (wt.%): (a) a non-steroidal antiinflammatory agent (0.1-1.0); (b) an alkyl-pyrrolidone (0.5-10); (c) hydrophilic polyethylene glycol (1-15); (d) a hydrophilic nonionic surfactant (0.01-3); (e) a water-soluble carboxylated polymer (2-15); (f) a water-soluble vinyl polymer (0.1-10); (g) a water-insoluble polyvalent metal salt (0.01-10); (h) a polyol (4-40); (i) an organic hydroxyacid; and (j) water.
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申请公布号 |
DE10026678(C1) |
申请公布日期 |
2002.03.21 |
申请号 |
DE20001026678 |
申请日期 |
2000.06.01 |
申请人 |
SANG-A PHARMACEUTICAL CO LTD., CHUNGCHEONG BUG-DO |
发明人 |
WOO, YANG PYO;CHO, SUNG MIN |
分类号 |
A61K9/70;A61K31/192;A61K31/196;A61K31/5415;A61K31/542;A61K47/00;A61K47/02;A61K47/10;A61K47/12;A61K47/22;A61K47/26;A61K47/32;A61P29/00;(IPC1-7):A61L15/44 |
主分类号 |
A61K9/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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