| 摘要 |
<p>Although glucose has been mainly employed in peritoneal dialysis for treating renal failure, there arises a problem that protein undergoes crosslinking due to the oxidation and denaturation of glucose and thus hardens peritoneal tissue, thereby making it impossible to continue the peritoneal dialysis. To overcome this problem, peritoneal dialysates containing a protein crosslinking inhibitor or an agent dissociating protein crosslinkage once formed are provided. As the protein crosslinking inhibitor or the agent dissociating protein crosslinkage once formed, it is effective to use reducing agents or antioxidants. These peritoneal dialysates are prepared by sterilizing peritoneal dialysates under elevated pressure at high temperature prior to the addition of the inhibitor(s), then individually sterilizing the inhibitor(s) and adding the same.</p> |
