MUTEINS OF THE CGRP 1-7 PEPTIDE FRAGMENT AND USE THEREOF AS NICOTINIC NEURONAL RECEPTOR ENHANCERS

摘要

Muteins of the Ser-Cys-Asn-Thr-Ala-Thr-Cys sequence from the N-terminal 1-7 fragment of the CGRP peptide, possessing an enhancing action on the activati on of neuronal nicotinic receptors, their pharmaceutical compositions containin g the same and their use for the potential therapy of neurological diseases ar e described.