MODIFIED DHPS GENES

摘要

The invention relates to modifications of biosynthesis key enzymes leading to essential amino acid accumulation in cells. A recombinant or isolated nucleic acid, or functional fragment thereof, encoding an enzyme dihydrodipicolinate synthase (DHPS), or functional fragment thereof, having been provided with a mutation leading to the replacement of at least one single amino acid residue with a cysteine residue.