发明名称 |
Process for producing optically active alcohol |
摘要 |
A novel process in which an optically active alcohol compound having a desired absolute configuration and a high optical purity can be obtained by asymmetrically hydrogenating a beta-keto acid compound through a simple operation. An optically active alcohol represented by general formula (III) as defined is obtained by asymmetrically hydrogenating a beta-keto ester compound represented by general formula (I) as defined in the presence of at least one ruthenium complex having as a ligand an optically active tertiary diphosphine compound represented by general formula (II) as defined.
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申请公布号 |
US2002035283(A1) |
申请公布日期 |
2002.03.21 |
申请号 |
US20010909803 |
申请日期 |
2001.07.23 |
申请人 |
TAKASAGO INTERNATIONAL CORPORATION |
发明人 |
SAITO TAKAO;YOKOZAWA TOHRU;MATSUMURA KAZUHIKO;SAYO NOBORU |
分类号 |
B01J31/24;C07B53/00;C07B61/00;C07C67/31;C07C67/39;C07C69/675;C07C69/732;C07C227/30;C07C229/22;(IPC1-7):C07C229/06;C07C69/62;C07C69/76 |
主分类号 |
B01J31/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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