发明名称 |
LIGANDS FOR METABOTROPIC GLUTAMATE RECEPTORS AND INHIBITORS OF NAALADASE |
摘要 |
The present invention relates to novel compounds and formulations thereof which compounds are ligands, e.g., agonists or antagonists, for a metabotropic glutamate receptor or a NAALADase enzyme or both. The present invention also relates to methods of modulating the activity o a metabotropic glutamate receptor or a NAALADase enzyme or both, e.g., in a subject in need thereof, using a compound or formulation of the present invention. The present invention also relates to methods of treating a subject suffering from a chronic or acute disease, malady or condition due at least in part to an abnormality in the activity of an endogenous metabotropic glutamate receptor or a NAALADase enzyme or both, using a compound or formulation of the present invention. |
申请公布号 |
WO0222627(A2) |
申请公布日期 |
2002.03.21 |
申请号 |
WO2001US28923 |
申请日期 |
2001.09.14 |
申请人 |
GEORGETWON UNIVERSITY |
发明人 |
KOZIKOWSKI, ALAN, P.;WROBLEWSKI, JARDA, T.;NAN, FAJUN |
分类号 |
A61P25/00;C07C59/347;C07C69/716;C07C271/22;C07C275/16;C07C275/26;C07C323/59;C07C335/08;C07D257/04;C07F9/30 |
主分类号 |
A61P25/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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