发明名称 |
Methods and compositions for enhancing the delivery of a nucleic acid to a cell |
摘要 |
The present invention relates to methods and compositions useful for enhancing the efficiency of delivery of a nucleic acid to a cell. Preferably the cell is a mammalian cell. The method comprises providing to a cell an agent capable of enhancing the cytoskeletal permissiveness of the cell for transfection. The method also comprises providing to the cell a nucleic acid delivery system for the transfection of the cell, whereby the efficiency of delivery of a nucleic acid to the cell is enhanced. Compositions and kits for enhancing the efficiency of delivery of a nucleic acid to a cell are also included
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申请公布号 |
US2002034821(A1) |
申请公布日期 |
2002.03.21 |
申请号 |
US20010851327 |
申请日期 |
2001.05.09 |
申请人 |
THE CHILDREN'S HOSPITAL OF PHILADELPHIA |
发明人 |
LEVY ROBERT J.;JONES PETER L.;LI QUANYI |
分类号 |
C12N15/09;A61K31/7088;A61K38/00;A61K48/00;A61P43/00;C12N15/87;(IPC1-7):A61K48/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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