发明名称 |
Metallic solid supports modified with nucleic acids |
摘要 |
The present invention is directed to solid supports having metallic surfaces comprising blocking moieties and modified nucleic acids, which exhibit excellent characteristics in hybridization assays, in a stable, reproducible, rapid manner. In an additional aspect, the invention provides methods utilizing the solid supports to hybridize probe nucleic acid to target nucleic acid and methods for detecting the hybridization complex.
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申请公布号 |
US2002034759(A1) |
申请公布日期 |
2002.03.21 |
申请号 |
US20010921645 |
申请日期 |
2001.08.03 |
申请人 |
CALIFORNIA INSTITUTE OF TECHNOLOGY |
发明人 |
MEADE THOMAS J.;KAYYEM JON F. |
分类号 |
C12N15/09;C07H21/00;C07H23/00;C12Q1/68;G01N33/566;(IPC1-7):C12Q1/68;C07H21/04;C12M1/34 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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