发明名称 |
HUMAN CARBAMYL PHOSPHATE SYNTHETASE I POLYMORPHISM AND DIAGNOSTIC AND THERAPEUTIC METHODS RELATING THERETO |
摘要 |
Isolated polynucleotide molecules and peptides encoded by these molecules are used in the analysis of human carbamyl phosphate synthetase I phenotypes, as well as in diagnostic and therapeutic applications, relating to a human carbamyl phosphate synthetase I polymorphism. By analyzing genomic DNA or amplified genomic DNA, or amplified cDNA derived from mRNA, it is possible to type a human carbamyl phosphate synthetase I with regard to the human carbamyl phosphate synthetase I polymorphism, for example, in the context of diagnosing and treating hepatic veno-occlusive disease (HVOD) associated with bone marrow transplants. |
申请公布号 |
EP1187844(A1) |
申请公布日期 |
2002.03.20 |
申请号 |
EP20000939475 |
申请日期 |
2000.06.01 |
申请人 |
VANDERBILT UNIVERSITY |
发明人 |
SUMMAR, MARSHALL, L.;CHRISTMAN, BRIAN, W. |
分类号 |
A61K38/00;C12N9/00;C12Q1/68;(IPC1-7):C07H21/04;C12N15/85;C07K16/00;C12N5/12;C12N15/00;C07K14/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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