| 发明名称 |
NON-PEPTIDE GNRH AGENTS, METHODS AND INTERMEDIATES FOR THEIR PREPARATION |
| 摘要 |
<p>Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin-releasing hormone are described. Such compounds and their pharmaceutically acceptable salts, multimers, prodrugs, and active metabolites are suitable for treating mammalian reproductive disorders and steroid hormone-dependent tumors as well as for regulating fertility, where suppression of gonadotropin release is indicated. Methods for synthesizing the compounds and intermediates useful in their preparation are also described.</p> |
| 申请公布号 |
LV12732(B) |
申请公布日期 |
2002.03.20 |
| 申请号 |
LV20010000045 |
申请日期 |
2001.03.16 |
| 申请人 |
AGOURON PHARMACEUTICALS, INC. |
发明人 |
ANDERSON,MARK BRIAN;VAZIR,HARESH N.;LUTHIN,DAVID ROBERT;PADERES,GENEVIEVE DEGUZMAN;PATHAK,VED P.;CHRISTIE,LANCE CHRISTOPHER;HONG,YUFENG;TOMPKINS,EILEEN VALENZUELA;LI,HAITAO;FAUST,JAMES |
| 分类号 |
C07D307/56;A61K31/34;A61K31/341;A61K31/352;A61K31/404;A61K31/4184;A61K31/427;A61K31/4375;A61K31/4427;A61K31/443;A61K31/4433;A61K31/496;A61K31/50;A61K31/501;A61K31/505;A61K31/506;A61K31/519;A61P5/02;A61P5/04;A61P13/08;A61P15/00;A61P15/16;A61P35/00;C07D307/68;C07D405/12;C07D405/14;C07D407/06;C07D409/12;C07D417/12;C07D471/04;C07D487/04;(IPC1-7):A61K31/34 |
主分类号 |
C07D307/56 |
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