| 摘要 |
PROBLEM TO BE SOLVED: To obtain an oral solid pharmaceutical formulation with pH-dependent multiphasic release containing a molecule useful in the inflammatory bowel disease therapy as an active ingredient. SOLUTION: This oral solid pharmaceutical formulation is an oral solid formulation containing a substance useful in the inflammatory bowel disease therapy as the active ingredient and is characterized by association of different polymers or mixtures of polymers, each one soluble starting from a pH value different from the others and ranging from 6 to 7, and by the multiphasic release of such the active ingredient, each phase occurring at a different pH value ranging from 6 to 7.
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