| 发明名称 |
Stabilized human papillomavirus formulations |
| 摘要 |
Human papillomavirus (HPV) antigen formulations are disclosed which prevent protein aggregation and show prolonged stability as aqueous solutions. These formulations comprise a salt (such as sodium chloride) and a non-ionic surfactant (Polysorbate 80 such as Tween 80(R)) in physiologically acceptable concentrations.
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| 申请公布号 |
US6358744(B1) |
申请公布日期 |
2002.03.19 |
| 申请号 |
US20000624482 |
申请日期 |
2000.07.24 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
VOLKIN DAVID B.;SHI LI;SANYAL GAUTAM |
| 分类号 |
A61K;A61K39/12;C07K14/025;C12N7/04;(IPC1-7):G01N31/00;A61K39/112 |
主分类号 |
A61K |
| 代理机构 |
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