发明名称 |
MULTIVALENT NEURAMINIDASE INHIBITOR CONJUGATES |
摘要 |
The invention relates to a multimeric compound or a pharmaceutically acceptable salt or derivative thereof which comprises three or more neuraminidase-binding groups attached to a spacer or linking group, in which the neuraminidase-binding group is a compound which binds to the active site of influenza virus neuraminidase, but is not cleaved by the neuraminidase. T he invention also relates to processes for the preparation of the multimeric compound defined above, pharmaceutical compositions containing them or metho ds for the treatment and/or prophylaxis of a viral infection involving them.</S DOAB>
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申请公布号 |
CA2416336(A1) |
申请公布日期 |
2002.03.14 |
申请号 |
CA20012416336 |
申请日期 |
2001.09.07 |
申请人 |
BIOTA SCIENTIFIC MANAGEMENT PTY LTD |
发明人 |
JIN, BETTY;WATSON, KEITH;MCCONNELL, DARRYL;WU, WEN-YANG;MASON, ANDREW MCMURTRIE;DOWLE, MICHAEL DENNIS;MACDONALD, SIMON JOHN FAWCETT |
分类号 |
A61K31/351;A61K31/496;A61K45/00;A61P31/12;A61P31/16;A61P43/00;C07D309/28;C07D405/14;C07D407/14;C07D493/04;C12Q1/04;C12Q1/70;G01N33/569;(IPC1-7):C07D407/14 |
主分类号 |
A61K31/351 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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