发明名称 |
HUMAN ANTIBODIES AGAINST <i>PSEUDOMONAS AERUGINOSA</i> LPS DERIVED FROM TRANSGENIC XENOMOUSE3 |
摘要 |
The invention described herein provides for human antibodies produced in non-human animals that specifically bind to Pseudomonas aeruginosa Lipopolysaccharide (LPS). The invention further provides methods for making the antibodies in a non-human animal, expression of the antibodies in cell lines including hybridomas and recombinant host cell systems. Also provided are kits and pharmaceutical compositions comprising the antibodies and methods of treating or preventing pseudomonas infection by administering to patient the pharmaceutical compositions described herein. |
申请公布号 |
WO0220619(A2) |
申请公布日期 |
2002.03.14 |
申请号 |
WO2001US28019 |
申请日期 |
2001.09.07 |
申请人 |
SCHREIBER, JOHN, R.;KAMBOJ, KULWANT, KAUER |
发明人 |
SCHREIBER, JOHN, R.;KAMBOJ, KULWANT, KAUER |
分类号 |
A01K67/027;A61K9/10;A61K9/107;A61K9/127;A61K9/72;A61K38/00;A61K39/395;A61K45/00;A61P3/10;A61P9/00;A61P11/00;A61P13/02;A61P17/00;A61P17/02;A61P19/04;A61P19/08;A61P27/02;A61P27/16;A61P29/00;A61P31/04;A61P35/00;A61P37/04;A61P41/00;A61P43/00;C07K16/12;C07K19/00;C12N1/19;C12N1/21;C12N5/10;C12N5/20;C12N15/02;C12N15/09;C12N15/13;C12N15/85;C12P21/02;C12P21/08;G01N33/569;G01N33/577 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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