| 发明名称 |
STAT3 AGONISTS AND ANTAGONISTS AND THERAPEUTIC USES THEREOF |
| 摘要 |
The present invention relates to methods of modulating, i.e., agonizing or antagonizing, Stat3 (Signal Transducer and Activator of Transcription3) signaling activity for use in gene therapy. Inhibition and/or activation of Stat3 signaling is an effective approach to modulate angiogenesis and the immune response for treatment and/or prevention of inflammation, infection, inflammation, immune disorders, and ischemia.
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| 申请公布号 |
WO0220032(A1) |
申请公布日期 |
2002.03.14 |
| 申请号 |
WO2001US28254 |
申请日期 |
2001.09.10 |
| 申请人 |
JOHN HOPKINS UNIVERSITY;UNIVERSITY OF SOUTH FLORIDA;YU, HUA;PARDOLL, DREW;JOVE, RICHARD;DALTON, WILLIAM |
发明人 |
YU, HUA;PARDOLL, DREW;JOVE, RICHARD;DALTON, WILLIAM |
| 分类号 |
A61K31/00;A61K38/00;A61K38/17;A61K38/20;A61K48/00;C07K14/47;G01N33/50;(IPC1-7):A61K38/00;A61K31/70;A61K45/00;A61K39/395;G01N33/53 |
主分类号 |
A61K31/00 |
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