发明名称 PURIFICATION PROCESS
摘要 There is disclosed a process for purifying a natural product using a two-phase, multi-solvent system followed by vacuum concentration and back extraction. The method allows for the removal of impurities by controlling the polarity balance of a two-phase system by manipulating the proportions of the four solvents and subsequently the relative distribution of the product versus the impurities.
申请公布号 WO0220618(A1) 申请公布日期 2002.03.14
申请号 WO2001US26782 申请日期 2001.08.28
申请人 MERCK & CO., INC.;ROUSH, DAVID, J.;GOKLEN, KENT, E.;CHANDLER, MARTIN, A.;LEE, STEVEN, S. 发明人 ROUSH, DAVID, J.;GOKLEN, KENT, E.;CHANDLER, MARTIN, A.;LEE, STEVEN, S.
分类号 C07K7/56;(IPC1-7):C07K16/00;C07K1/14;A23J1/00 主分类号 C07K7/56
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