ANTIGENIC FRAGMENTS ASSOCIATED WITH STRESS-INDUCED PROTEINS AND THEIR USE AS VACCINES

摘要

The present invention relates to a method for isolating and identifying specific immunogenic pathogen-specific peptides associated with stress proteins induced by the treatment of pathogens and pathogen-infected cells with stress inducing stimuli. The invention also relates to the use of the antigenic fragments derived from complexes thereof with heat shock or other stresses proteins as the immunogenic determinant in vaccine compositions.