The present invention relates to a newly identified human soluble adenylyl cyclase and nucleic acid sequences encoding the adenylyl cyclase. The invention further relates to methods of using the adenylyl cyclase polypeptides and polynucleotides as a targets for identifying agonists and antagonists that are selective for human soluble adenylyl cyclase. Inhibitors of human soluble adenylyl cyclase can be used as contraceptive agents.
申请公布号
WO0220745(A1)
申请公布日期
2002.03.14
申请号
WO2001US27391
申请日期
2001.09.05
申请人
UNIVERSITY OF VIRGINIA PATENT FOUNDATION;HERR, JOHN, C.;VISCONTI, PABLO;MANDAL, ARABINDA;KHOLE, VRINDA