摘要 |
Methods are disclosed for establishing a relationship between spectral properties of molecules and biological, chemical, and physical endpoints of the molecules. Spectral data including data from nuclear magnetic resonance, mass spectrometric, infrared, and ultraviolet-visible techniques are used along with endpoint data to train a pattern-recognition program. The training yields a spectral data-activity relationship that may be used to predict the endpoint properties of a molecule from its spectral data alone. Methods for rapidly screening isolated compounds or mixtures of compounds based upon their spectral data are included. |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES, THE NATIONAL INSTITUTES OF HEALTH;MILLER, DWIGHT, W.;BEGER, RICHARD;LAY, JACKSON, O., JR.;WILKENS, JON, G.;FREEMAN, JAMES, P. |
发明人 |
MILLER, DWIGHT, W.;BEGER, RICHARD;LAY, JACKSON, O., JR.;WILKENS, JON, G.;FREEMAN, JAMES, P. |