| 发明名称 |
ENZYMES HAVING HIGH TEMPERATURE POLYMERASE ACTIVITY AND METHODS OF USE THEREOF |
| 摘要 |
The invention relates to thermostable polymerases that have polymerase activity temperatures in the range from 9~ C up to 113~ C, such as those derived from Pyrolobus fumaria, and to polynucleotides encoding the polymerases In addition, methods of designing new thermostable DNA polymeras es and methods of use thereof are also provided. The polymerases have increased activity and stability at increased pH and temperature.
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| 申请公布号 |
CA2419975(A1) |
申请公布日期 |
2002.03.14 |
| 申请号 |
CA20012419975 |
申请日期 |
2001.09.06 |
| 申请人 |
DIVERSA CORPORATION |
发明人 |
SHORT, JAY M.;MATHUR, ERIC J.;CALLEN, WALTER |
| 分类号 |
C12N15/09;C07K16/40;C12M1/00;C12N9/12;C12N15/54;C12P19/34;C12P21/08;C12Q1/48;C12Q1/68;G06F17/30;(IPC1-7):C12N9/12;C12N15/10;C12N15/11;G06F17/50 |
主分类号 |
C12N15/09 |
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