Compositions and methods for the generation of single stranded cdna microarrays with accurate universal quantitation reference

摘要

Single stranded nucleic acid oligonucleotides are immobilized on a solid support to provide a DNA chip, or microarray of single stranded DNA immobilized on a solid support, for hybridizing oligonucleotides. A universal and quantitatively reproducible hybridization reference oligonucleotide is used for data normalization and for quality control of the array printing process.